Lion’s Mane Hericium erinaceus, triggers neurite outgrowth and regeneration of damaged nerves. Its polysaccharides help with neuronal differentiation and promote neuronal survival. It has been found to help after ischemic strokes to prevent cell death and to help cells recover their health after loss of blood supply. Cognitive function scale scores increase continuously with intake.

Curcumin (Turmeric) is Indian herb used from ancient times and still used in curry powder. It has been extensively studied in modern medicine and Indian systems of medicine for the treatment of various medical conditions, including cystic fibrosis, haemorrhoids, gastric ulcer, colon cancer, breast cancer, atherosclerosis, liver diseases and arthritis. It has been used in various types of treatments for dementia and traumatic brain injury.

• Curcumin has a potential role in the prevention and treatment of Alzeheimer's Disease. Curcumin as an antioxidant, anti-inflammatory and lipophilic action improves the cognitive functions in patients with AD. A growing body of evidence indicates that oxidative stress, free radicals, beta amyloid, cerebral deregulation caused by bio-metal toxicity and abnormal inflammatory reactions contribute to the key event in Alzheimer's disease pathology. Due to various effects of curcumin, such as decreased Beta-amyloid plaques, delayed degradation of neurons, metal-chelation, anti-inflammatory, antioxidant and decreased microglia formation, the overall memory in patients with Alzheimer's Disease has improved
• Curcumin can boost brain-derived neurotrophic factor. One of the main drivers in the process of plasticity (making new brain connections, IE, learning) is brain-derived neurotrophic factor (BDNF).
• Curcumin has shown some promise in treating depression. In a controlled trial, 60 people with depression were randomized into three groups. One group took Prozac, another group took 1 gram of curcumin, and the third group took both Prozac and curcumin. After 6 weeks, curcumin had led to improvements similar to those of Prozac.

Lemon Balm has helped in numerous studies to delay and/or completely prevent Alzheimer's processes.

Bacopa monnieri is an ancient herb used in Ayurvedic medicine to enhance brain function. Several studies have found that Bacopa monnieri supplements can speed up information processing in your brain, reduce reaction times and improve memory.

Red Wine concentrate has been shown to protect against decline in neural activity in those parts of the brain that typically decline once dementia has begun. The is important because the earlier one intervenes with red wine concentrate supplementation the less damage will occur.